Confidence:StrongSolidPlausibleTentativeSpeculative

• Bloodline Recollector // Ancestral Craving

  1BB

  Creature — Vampire Warlock // InstantB

  Sanctum Guardian is a sacrifice outlet, enabling Bloodline Recollector's death or sacrifice trigger.
• The Meathook Massacre

  XBB

  Legendary EnchantmentB

  Sanctum Guardian is a sacrifice outlet, enabling The Meathook Massacre's death or sacrifice trigger.
• The Serpent Society

  1BG

  Legendary Creature — Human Snake VillainBG

  Sanctum Guardian is a sacrifice outlet, enabling The Serpent Society's death or sacrifice trigger.
• Bequeathal

  G

  Enchantment — AuraG

  Sanctum Guardian is a sacrifice outlet, enabling Bequeathal's death or sacrifice trigger.
• Syr Vondam, Sunstar Exemplar

  WB

  Legendary Creature — Human KnightBW

  Sanctum Guardian is a sacrifice outlet, enabling Syr Vondam, Sunstar Exemplar's death or sacrifice trigger.
• Bruce Banner // The Incredible Hulk

  U2RRGG

  Legendary Creature — Human Scientist Hero // Legendary Creature — Gamma Berserker HeroGRU

  Bruce Banner grants an extra combat phase, enabling Sanctum Guardian's combat-trigger payoff.
• Shaile, Dean of Radiance // Embrose, Dean of Shadow

  1W2BB

  Legendary Creature — Bird Cleric // Legendary Creature — Human WarlockBW

  Sanctum Guardian is a sacrifice outlet, enabling Shaile, Dean of Radiance's death or sacrifice trigger.
• Malicious Affliction

  BB

  InstantB

  Sanctum Guardian is a sacrifice outlet, enabling Malicious Affliction's death or sacrifice trigger.
• Enduring Renewal

  2WW

  EnchantmentW

  Sanctum Guardian is a sacrifice outlet, enabling Enduring Renewal's death or sacrifice trigger.
• Liliana, Heretical Healer // Liliana, Defiant Necromancer

  1BB

  Legendary Creature — Human Cleric // Legendary Planeswalker — LilianaB

  Sanctum Guardian is a sacrifice outlet, enabling Liliana, Heretical Healer's death or sacrifice trigger.
• Skullclamp

  1

  Artifact — EquipmentC

  Sanctum Guardian is a sacrifice outlet, enabling Skullclamp's death or sacrifice trigger.
• Kaya's Ghostform

  B

  Enchantment — AuraB

  Sanctum Guardian is a sacrifice outlet, enabling Kaya's Ghostform's death or sacrifice trigger.
• Ob Nixilis, Unshackled

  4BB

  Legendary Creature — DemonB

  Sanctum Guardian is a sacrifice outlet, enabling Ob Nixilis, Unshackled's death or sacrifice trigger.
• Meltstrider Eulogist

  2G

  Creature — Insect SoldierG

  Sanctum Guardian is a sacrifice outlet, enabling Meltstrider Eulogist's death or sacrifice trigger.
• All-Out Assault

  2RWB

  EnchantmentBRW

  All-Out Assault grants an extra combat phase, enabling Sanctum Guardian's combat-trigger payoff.
• Aggravated Assault

  2R

  EnchantmentR

  Aggravated Assault grants an extra combat phase, enabling Sanctum Guardian's combat-trigger payoff.
• Sifa Grent

  3BR

  Legendary Planeswalker — SifaBR

  Sanctum Guardian is a sacrifice outlet, enabling Sifa Grent's death or sacrifice trigger.
• Chandra, Flamecaller

  4RR

  Legendary Planeswalker — ChandraR

  Chandra, Flamecaller deals damage to many targets, fueling Sanctum Guardian's damage-payoff trigger.
• Mila, Crafty Companion // Lukka, Wayward Bonder

  1WW4RR

  Legendary Creature — Fox // Legendary Planeswalker — LukkaRW

  Mila, Crafty Companion produces broad damage that redirects through Sanctum Guardian into something useful.
• Sticky Fingers

  R

  Enchantment — AuraR

  Sanctum Guardian is a sacrifice outlet, enabling Sticky Fingers's death or sacrifice trigger.
• Elas il-Kor, Sadistic Pilgrim

  WB

  Legendary Creature — Phyrexian Kor ClericBW

  Sanctum Guardian is a sacrifice outlet, enabling Elas il-Kor, Sadistic Pilgrim's death or sacrifice trigger.
• Fires of Mount Doom

  2R

  Legendary EnchantmentR

  Fires of Mount Doom produces broad damage that redirects through Sanctum Guardian into something useful.
• Skin Invasion // Skin Shedder

  R

  Enchantment — Aura // Creature — Insect HorrorR

  Sanctum Guardian is a sacrifice outlet, enabling Skin Invasion's death or sacrifice trigger.
• Athreos, God of Passage

  1WB

  Legendary Enchantment Creature — GodBW

  Sanctum Guardian is a sacrifice outlet, enabling Athreos, God of Passage's death or sacrifice trigger.
• Avarice Amulet

  4

  Artifact — EquipmentC

  Sanctum Guardian is a sacrifice outlet, enabling Avarice Amulet's death or sacrifice trigger.