Confidence:StrongSolidPlausibleTentativeSpeculative

• Humility

  2WW

  EnchantmentW

  Toughness wipe: one card sets every other creature's base toughness to 1 (or another small number), and the other repeatedly kills anything that small — a standing -1/-1, damage to each creature, or a pinger that untaps when a creature dies. Together they wipe the board and kill whatever enters after (once, if the toughness change only lasts the turn).
• Maha, Its Feathers Night

  3BB

  Legendary Creature — Elemental BirdB

  Toughness wipe: one card sets every other creature's base toughness to 1 (or another small number), and the other repeatedly kills anything that small — a standing -1/-1, damage to each creature, or a pinger that untaps when a creature dies. Together they wipe the board and kill whatever enters after (once, if the toughness change only lasts the turn).
• Overwhelming Splendor

  6WW

  Enchantment — Aura CurseW

  Toughness wipe: one card sets every other creature's base toughness to 1 (or another small number), and the other repeatedly kills anything that small — a standing -1/-1, damage to each creature, or a pinger that untaps when a creature dies. Together they wipe the board and kill whatever enters after (once, if the toughness change only lasts the turn).
• Godhead of Awe

  W/UW/UW/UW/UW/U

  Creature — Spirit AvatarUW

  Toughness wipe: one card sets every other creature's base toughness to 1 (or another small number), and the other repeatedly kills anything that small — a standing -1/-1, damage to each creature, or a pinger that untaps when a creature dies. Together they wipe the board and kill whatever enters after (once, if the toughness change only lasts the turn).
• Bloodline Recollector // Ancestral Craving

  1BB

  Creature — Vampire Warlock // InstantB

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Bloodline Recollector's death-trigger or removal payoff.
• Chevill, Bane of Monsters

  BG

  Legendary Creature — Human RogueBG

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Chevill, Bane of Monsters's death-trigger or removal payoff.
• Private Research

  U

  Enchantment — AuraU

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Private Research's death-trigger or removal payoff.
• Quest for the Gravelord

  B

  EnchantmentB

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Quest for the Gravelord's death-trigger or removal payoff.
• Bequeathal

  G

  Enchantment — AuraG

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Bequeathal's death-trigger or removal payoff.
• Eye of Singularity

  3W

  World EnchantmentW

  Both cards trigger when a creature enters the battlefield — they fire together.
• Kraven the Hunter

  1BG

  Legendary Creature — Human Warrior VillainBG

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Kraven the Hunter's death-trigger or removal payoff.
• Lagomos, Hand of Hatred

  1BR

  Legendary Creature — Human ShamanBR

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Lagomos, Hand of Hatred's death-trigger or removal payoff.
• Enduring Renewal

  2WW

  EnchantmentW

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Enduring Renewal's death-trigger or removal payoff.
• Fire Lord Zuko

  RWB

  Legendary Creature — Human Noble AllyBRW

  Both cards trigger when a creature enters the battlefield — they fire together.
• Eater of Virtue

  1

  Legendary Artifact — EquipmentC

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Eater of Virtue's death-trigger or removal payoff.
• Skullclamp

  1

  Artifact — EquipmentC

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Skullclamp's death-trigger or removal payoff.
• Lagrella, the Magpie

  GWU

  Legendary Creature — Human SoldierGUW

  Both cards trigger when a creature enters the battlefield — they fire together.
• Malicious Affliction

  BB

  InstantB

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Malicious Affliction's death-trigger or removal payoff.
• Prowl, Stoic Strategist // Prowl, Pursuit Vehicle

  3W

  Legendary Artifact Creature — Robot // Legendary Artifact — VehicleW

  Both cards trigger when a creature enters the battlefield — they fire together.
• Archon of Sun's Grace

  2WW

  Creature — ArchonW

  Both cards trigger when a creature enters the battlefield — they fire together.
• April O'Neil, Live on the Scene

  1U

  Legendary Creature — Human DetectiveU

  Both cards trigger when a creature enters the battlefield — they fire together.
• Elvish Archivist

  1G

  Creature — Elf ArtificerG

  Both cards trigger when a creature enters the battlefield — they fire together.
• Athreos, God of Passage

  1WB

  Legendary Enchantment Creature — GodBW

  Doomwake Giant can kill creatures (with damage or by shrinking them), enabling Athreos, God of Passage's death-trigger or removal payoff.
• Elesh Norn, Mother of Machines

  4W

  Legendary Creature — Phyrexian PraetorW

  Elesh Norn, Mother of Machines makes Doomwake Giant's triggered ability trigger an additional time — each time it fires, you get it twice. Value, not a loop.
• Virtue of Knowledge // Vantress Visions

  4U1U

  Enchantment // Instant — AdventureU

  Virtue of Knowledge makes Doomwake Giant's triggered ability trigger an additional time — each time it fires, you get it twice. Value, not a loop.