Confidence:StrongSolidPlausibleTentativeSpeculative

• Minsc & Boo, Timeless Heroes

  2RG

  Legendary Planeswalker — MinscGR

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Minsc & Boo, Timeless Heroes sacrifices it — the opponent loses the permanent for good.
• Fiend Artisan

  B/GB/G

  Creature — NightmareBG

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Fiend Artisan sacrifices it — the opponent loses the permanent for good.
• Prime Speaker Vannifar

  2GU

  Legendary Creature — Elf Ooze WizardGU

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Prime Speaker Vannifar sacrifices it — the opponent loses the permanent for good.
• Kethek, Crucible Goliath

  2BR

  Legendary Creature — Phyrexian BeastBR

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Kethek, Crucible Goliath sacrifices it — the opponent loses the permanent for good.
• Viscerid Drone

  1U

  Creature — Homarid DroneU

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Viscerid Drone sacrifices it — the opponent loses the permanent for good.
• Invasion of New Capenna // Holy Frazzle-Cannon

  WB

  Battle — Siege // Artifact — EquipmentBW

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Invasion of New Capenna sacrifices it — the opponent loses the permanent for good.
• My Precious // Allure of Power

  31B

  Legendary Artifact — Equipment // Instant — AdventureB

  Chamber of Manipulation temporarily takes control of an opponent's creature, and My Precious sacrifices it — the opponent loses the permanent for good.
• Caesar, Legion's Emperor

  1RWB

  Legendary Creature — Human SoldierBRW

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Caesar, Legion's Emperor sacrifices it — the opponent loses the permanent for good.
• Grimgrin, Corpse-Born

  3UB

  Legendary Creature — Zombie WarriorBU

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Grimgrin, Corpse-Born sacrifices it — the opponent loses the permanent for good.
• Garruk Relentless // Garruk, the Veil-Cursed

  3G

  Legendary Planeswalker — Garruk // Legendary Planeswalker — GarrukBG

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Garruk Relentless sacrifices it — the opponent loses the permanent for good.
• Innocuous Researcher

  3G

  Creature — Centaur DetectiveG

  Innocuous Researcher untaps all (or many) permanents, refreshing Chamber of Manipulation's tap activation.
• Cabal Therapist

  B

  Creature — HorrorB

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Cabal Therapist sacrifices it — the opponent loses the permanent for good.
• Mask of the Mimic

  U

  InstantU

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Mask of the Mimic sacrifices it — the opponent loses the permanent for good.
• Fiery Gambit

  2R

  SorceryR

  Fiery Gambit untaps all (or many) permanents, refreshing Chamber of Manipulation's tap activation.
• Zimone and Dina

  BGU

  Legendary Creature — Human DryadBGU

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Zimone and Dina sacrifices it — the opponent loses the permanent for good.
• Louisoix's Sacrifice

  U

  InstantU

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Louisoix's Sacrifice sacrifices it — the opponent loses the permanent for good.
• Hidetsugu, Devouring Chaos

  3B

  Legendary Creature — Ogre DemonBR

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Hidetsugu, Devouring Chaos sacrifices it — the opponent loses the permanent for good.
• Vivien on the Hunt

  4GG

  Legendary Planeswalker — VivienG

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Vivien on the Hunt sacrifices it — the opponent loses the permanent for good.
• Jorn, God of Winter // Kaldring, the Rimestaff

  2G1UB

  Legendary Snow Creature — God // Legendary Snow ArtifactBGU

  Jorn, God of Winter untaps all (or many) permanents, refreshing Chamber of Manipulation's tap activation.
• Grist, the Hunger Tide

  1BG

  Legendary Planeswalker — GristBG

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Grist, the Hunger Tide sacrifices it — the opponent loses the permanent for good.
• Greed's Gambit

  3B

  EnchantmentB

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Greed's Gambit sacrifices it — the opponent loses the permanent for good.
• Fain, the Broker

  2B

  Legendary Creature — Human WarlockB

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Fain, the Broker sacrifices it — the opponent loses the permanent for good.
• Tevesh Szat, Doom of Fools

  4B

  Legendary Planeswalker — SzatB

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Tevesh Szat, Doom of Fools sacrifices it — the opponent loses the permanent for good.
• Ashnod, Flesh Mechanist

  B

  Legendary Creature — Human ArtificerB

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Ashnod, Flesh Mechanist sacrifices it — the opponent loses the permanent for good.
• Fireblade Artist

  BR

  Creature — Human ShamanBR

  Chamber of Manipulation temporarily takes control of an opponent's creature, and Fireblade Artist sacrifices it — the opponent loses the permanent for good.